A fundamental study of the primary atomisation mechanism and aerosol plume development of the pressurised metered dose inhaler

A fundamental study of the primary atomisation mechanism and aerosol plume development of the pressurised metered dose inhaler

The pressurised metered dose inhaler (pMDI) is the most popular device for delivery of inhaled therapeutic aerosols to the lungs for treatment of asthma and COPD. One significant weakness of the pMDI is the high level of oropharyngeal deposition leading to low drug delivery efficiency. With the incr...

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Bibliographic Details
Main Author: Ben Myatt
Format: Default Thesis
Published: 2017
Subjects:
Mechanical engineering not elsewhere classified
Pressurised Metered Dose Inhaler
pMDI
Metered Dose Inhaler
Inhaler
Phase Doppler Anomometry
PDA
Particle Image Velocimetry
PIV
Atomisation
Atomization
Atomisation mechanism
Atomization mechanism
Aerosol plume development
HFA134
HFA227
HFA134-ethanol
HFA134/ethanol
Asthma
COPD
Optical diagnostics
Optical diagnostic techniques
Flow visualisation
Internal flow visualisation
External flow visualisation
Schlieren
Schlieren imaging
Spray plume
Aerosol
Aerosol plume
High speed imaging
Plume characterisation
Spray characterisation
Droplet size
Velocity
Speed
Mechanical Engineering not elsewhere classified
Online Access:https://hdl.handle.net/2134/27530
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https://hdl.handle.net/2134/27530

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