Dynamic kinetic resolution in the asymmetric synthesis of β-amino acids by organocatalytic reduction of enamines with trichlorosilane

A new methodology based on the organocatalytic asymmetric hydrosilylation of enamines that allows a direct access to a range of β and β -amino acid derivatives was presented. The results show a successful reduction of aromatic substrates, a sterically more hindered ortho-substituted derivatives, and...

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Bibliographic Details
Main Authors: Andrei Malkov, Sigitas Stoncius, Kvetoslava Vrankova, Matthias Arndt, Pavel Kocovsky
Format: Default Article
Published: 2008
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Online Access:https://hdl.handle.net/2134/13546
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