Combined optimization of start-up shutdown and grade transition of a multistage continuous crystallization process

Continuous pharmaceutical campaigns may exhibit extremely short operating windows. As a result, the impact of the start-up and shutdown on both costs of production and environmental footprint is extremely important. In this paper, a systematic model-based dynamic optimization strategy was developed...

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Bibliographic Details
Main Authors: Jiaxu Liu, Brahim Benyahia
Format: Default Conference proceeding
Published: 2022
Subjects:
Online Access:https://hdl.handle.net/2134/19328954.v1
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