Abstract 19810: Characterization of Lesions Created by a Heated, Saline Irrigated Needle-Tip Catheter in the Normal and Infarcted Canine Heart

BackgroundInability to eliminate intramural arrhythmogenic substrates is one of the reasons for recurrent VT after catheter ablation in patients with sustained ventricular tachycardia (VT). The aim of the present study was to evaluate intramural lesion formation using a SERF (saline enhanced radiofr...

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Published in:Circulation (New York, N.Y.) N.Y.), 2016-11, Vol.134 (Suppl_1 Suppl 1), p.A19810-A19810
Main Authors: Suzuki, Atsushi, Lehmann, H Immo, Wang, Songyun, Parker, Kay D, Rettmann, Maryam, Viker, Kimberly B, Johnson, Susan B, Packer, Douglas L
Format: Article
Language:English
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Summary:BackgroundInability to eliminate intramural arrhythmogenic substrates is one of the reasons for recurrent VT after catheter ablation in patients with sustained ventricular tachycardia (VT). The aim of the present study was to evaluate intramural lesion formation using a SERF (saline enhanced radiofrequency) needle-tip catheter, compared to a conventional ablation catheter in normal and dogs with healed myocardial infarction (MI).Methods and ResultsTwenty-two adult mongrel dogs (30-40 kg, 15 normal, 7 MI group) were studied. Lesions were created using the SERF catheter or a standard contact force catheter (SC) in normal and MI dogs. Comparing SERF to SC ablation, SERF (40W/50°C) produced larger lesion volumes than the SC - even with contact force (CF) of >20g - in both normal and infarcted left ventricular (LV) myocardium (983.1±905.8 vs. 461.9±178.3 mm; p=0.005, normal dogs, 1052.3±543.0 vs. 340.3±160.5 mm; p20g in both groups (59.1% vs. 7.7%; p=0.001, normal dogs, 60.0% vs. 12.5%; p=0.029, MI dogs). Using SERF, the mean depth of ablated lesions reached 90% of the LV wall in both normal and MI dogs (Figure 1B and 2B). Comparing SERF lesions (40W/50°C), in normal to lesions in myocardium with infarct scar, there were no significant difference in lesion volume (p=0.338).ConclusionsThe SERF catheter created more often transmural and larger ablative lesions in both normal and infarcted canine myocardium. SERF ablation size does not seem to be affected by the presence of scar tissue.
ISSN:0009-7322
1524-4539