Supramolecular Heterodimer Peptides Assembly for Nanoparticles Functionalization (Adv. Healthcare Mater. 15/2024)

Biofunctionalization In article 2304250, Alexandre Detappe and co‐workers report a novel biofunctionalization strategy for nanoparticles to enhance their tumor targeting efficiency based on supramolecular assembly of heterotetramers displaying VHHs. They validated in vitro and in vivo this Legolike...

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Bibliographic Details
Published in:Advanced healthcare materials 2024-06, Vol.13 (15), p.n/a
Main Authors: Mathieu, Clélia, Ghosh, Shayamita, Draussin, Julien, Gasser, Adeline, Jacquot, Guillaume, Banerjee, Mainak, Gupta, Tanushree, Schmutz, Marc, Mirjolet, Céline, Tillement, Olivier, Lux, François, Klymchenko, Andrey S., Donzeau, Mariel, Pivot, Xavier, Harlepp, Sébastien, Detappe, Alexandre
Format: Article
Language:English
Online Access:Get full text
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Summary:Biofunctionalization In article 2304250, Alexandre Detappe and co‐workers report a novel biofunctionalization strategy for nanoparticles to enhance their tumor targeting efficiency based on supramolecular assembly of heterotetramers displaying VHHs. They validated in vitro and in vivo this Legolike approach using various nanoparticles and VHHs, demonstrating enhanced tumor uptake, retention, and diffusion.
ISSN:2192-2640
2192-2659
DOI:10.1002/adhm.202470096