4-ACETYLAPLYKURODIN-B AND APLYKURODINONE-B, 2 ICHTHYOTOXIC DEGRADED STEROLS FROM THE MEDITERRANEAN MOLLUSK APLYSIA-FASCIATA

Two ichthyotoxic lactones, 4-acetylaplykurodin B [1] and aplykurodinone B [2], were isolated from the external parts of the body of the mollusk Aplysia fasciata. Their structures, determined by spectroscopic and chemical means, are closely related to aplykurodin B [3] previously isolated from Aplysi...

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Bibliographic Details
Published in:Journal of natural products (Washington, D.C.) D.C.), 1992-07, Vol.55 (7), p.989-993
Main Authors: SPINELLA, A, GAVAGNIN, M, CRISPINO, A, CIMINO, G, MARTINEZ, E, ORTEA, J, SODANO, G
Format: Article
Language:English
Subjects:
Chemistry, Medicinal
Life Sciences & Biomedicine
Pharmacology & Pharmacy
Plant Sciences
Science & Technology
Online Access:Get full text
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Summary:Two ichthyotoxic lactones, 4-acetylaplykurodin B [1] and aplykurodinone B [2], were isolated from the external parts of the body of the mollusk Aplysia fasciata. Their structures, determined by spectroscopic and chemical means, are closely related to aplykurodin B [3] previously isolated from Aplysia kurodai. The interconversion of delta- and gamma-lactones in the aplykurodin derivatives has been also investigated.
ISSN:0163-3864
DOI:10.1021/np50085a027