A NEW MACROCYCLIC LACTAM ANTIBIOTIC, BE-14106 .1. TAXONOMY, ISOLATION, BIOLOGICAL-ACTIVITY AND STRUCTURAL ELUCIDATION

A Streptomyces strain labeled A14106 was isolated and found to produce a novel 20-membered macrocyclic lactam derivative, BE-14106, which exhibited both cytotoxic activity against murine tumor cell lines and antimicrobial activity.

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Bibliographic Details
Published in:Journal of antibiotics 1992-06, Vol.45 (6), p.868-874
Main Authors: KOJIRI, K, NAKAJIMA, S, SUZUKI, H, KONDO, H, SUDA, H
Format: Article
Language:English
Subjects:
Biotechnology & Applied Microbiology
Immunology
Life Sciences & Biomedicine
Microbiology
Pharmacology & Pharmacy
Science & Technology
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Description
Summary:A Streptomyces strain labeled A14106 was isolated and found to produce a novel 20-membered macrocyclic lactam derivative, BE-14106, which exhibited both cytotoxic activity against murine tumor cell lines and antimicrobial activity.
ISSN:0021-8820
DOI:10.7164/antibiotics.45.868