Gender disparity in early death after ST-elevation myocardial infarction

Background Females with acute myocardial infarction （AMI） have a higher risk of adverse outcomes because of receiving less evidence-based medical care. Our aim was to investigate the gender disparity in early death after ST- elevation myocardial infarction （STEMI） in the current era. Methods A total...

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Bibliographic Details
Published in:Chinese medical journal 2013, Vol.126 (18), p.3481-3485
Main Authors: Zhang, Bo, Zhang, Wei, Huang, Rong-Chong, Zhang, Yan, Liu, Jun, Zheng, Zheng-Guo, Jiang, Da-Ming, Sun, Yu-Jiao, Ren, Li-Na, Zhou, Xu-Chen, Qi, Guo-Xian
Format: Article
Language:English
Subjects:
Aged
Angioplasty, Balloon, Coronary
Female
Hospital Mortality
Humans
Logistic回归分析
Male
Middle Aged
Myocardial Infarction - mortality
Myocardial Infarction - therapy
Risk Factors
Sex Factors
危险因素
差距
急性心肌梗死
性别
早期死亡
死亡率
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Summary:Background Females with acute myocardial infarction （AMI） have a higher risk of adverse outcomes because of receiving less evidence-based medical care. Our aim was to investigate the gender disparity in early death after ST- elevation myocardial infarction （STEMI） in the current era. Methods A total of 1429 consecutive patients with STEMI in the Liaoning district were analyzed. We compared hospital care and cardiac event data by sex for in-patients with acute STEMI within 24 hours of symptom onset. Results In the emergency reperfusion group （n=754）, in-hospital mortality occurred in 4.2% of the males and 11.2% of the females （P=-0.001）. In the non-emergency reperfusion group （n=675）, in-hospital mortality occurred in 13.0% of the males and 22.9% of the females （P=-0.001）. Multivariate Logistic regression analysis revealed female sex as an independent risk factor of death for STEMI patients during hospitalization （OR=1.691, P=0.007）. After controlling for patients who died within 24 hr after admission, female sex was no longer an independent risk factor （OR=1.409, P=0.259）. Conclusion Female sex was an independent risk factor for in-hospital mortality of STEMI patients, which is explained by an excess of very early deaths.
ISSN:0366-6999
2542-5641
DOI:10.3760/cma.j.issn.0366-6999.20130381