Simultaneous determination of 14β-lactam antibiotics in cosmetic products by liquid chromatography tandem mass spectrometry method

In this study,a simple and rapid high-performance liquid chromatography-tandem mass spectrometry（HPLC-MS/MS） method was established and validated to determine the 14β-lactam antibiotics in cosmetic products,including 1（ceftazidime）,2（cefaclor）, 3（cefdinir）,4（ampicillin）,5（cefalexin）,6（ceftezole）,7（c...

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Bibliographic Details
Published in:Chinese chemical letters 2011-03, Vol.22 (3), p.334-337
Main Authors: Wu, Cai Sheng, Zhang, Jin Lan, Qiao, Yan Ling, Wang, Yi Lin, Chen, Zhi Rong
Format: Article
Language:English
Subjects:
Cosmetic
High-performance liquid chromatography–tandem mass spectrometry (HPLC–MS/MS)
β-Lactam antibiotics
串联质谱法
内酰胺类
化妆品
同时测定
头孢他啶
抗生素
氨苄青霉素
高效液相色谱
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Summary:In this study,a simple and rapid high-performance liquid chromatography-tandem mass spectrometry（HPLC-MS/MS） method was established and validated to determine the 14β-lactam antibiotics in cosmetic products,including 1（ceftazidime）,2（cefaclor）, 3（cefdinir）,4（ampicillin）,5（cefalexin）,6（ceftezole）,7（cefotaxim）,8（cefradine）,9（cefuroxime）,10（cephazoline）,11 （cefathiamidine）,12（cefoperazone）,13（cafalotin）,14（piperacillin）.
ISSN:1001-8417
1878-5964
DOI:10.1016/j.cclet.2010.09.035