External root resorption (EARR) and interleukin-1β (rs1143634) gene polymorphism in the Bataknese population: A pilot study

External apical root resorption (EARR) is a condition that frequently arises after orthodontic treatment. Interleukin 1 (IL-1) is the gene responsible for the initiation of bone resorption and activating the osteoclasts, and is responsible for the potential of root resorption development. This study...

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Bibliographic Details
Main Authors: Bahirrah, Siti, Lestari, Widya, Zulhakim, Amir, Suwandi, Asrul, Irfanita, Nining
Format: Conference Proceeding
Language:English
Subjects:
Cytokines
Interleukins
Nucleotides
Orthodontics
Polymerase chain reaction
Polymorphism
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Summary:External apical root resorption (EARR) is a condition that frequently arises after orthodontic treatment. Interleukin 1 (IL-1) is the gene responsible for the initiation of bone resorption and activating the osteoclasts, and is responsible for the potential of root resorption development. This study investigated the presence of a single nucleotide polymorphism (rs1143634) in IL-1β gene and its relationship with root resorption in 20 individuals of Bataknese background. Panoramic radiographs of all patients were taken before and after orthodontic treatment. Subjects were classified as either EARR ≥2mm or EARR
ISSN:0094-243X
1551-7616
DOI:10.1063/5.0115002