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The spectral investigations of interaction between high-molecular proteins and small adenine derivates

The spectral properties of co-systems of the DNA, RNA, and small nucleotide derivates with high-molecular π-electron-containing proteins were investigated. The positions of the first excited electronic energy levels of these compounds were verified. AT-complex in the DNA, adenine groups in the RNA/o...

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Bibliographic Details
Published in:Low temperature physics (Woodbury, N.Y.) N.Y.), 2022-04, Vol.48 (4), p.318-321
Main Authors: Kudrya, V. Yu, Yashchuk, V. M., Tkachuk, Z. Yu, Gumenyuk, Ya. O., Naumenko, A. P.
Format: Article
Language:English
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Summary:The spectral properties of co-systems of the DNA, RNA, and small nucleotide derivates with high-molecular π-electron-containing proteins were investigated. The positions of the first excited electronic energy levels of these compounds were verified. AT-complex in the DNA, adenine groups in the RNA/oligoadenylate, and tryptophane groups in the proteins were examined as the main triplet electronic excitations traps. The changes in fluorescence and phosphorescence spectra of the co-systems mentioned above under a variation of mutual concentrations of the oligoadenylate and protein macromolecules were observed. The spectral response of the binding of the oligoadenylate to the proteins (Human Albumin, Interferon, Immunoglobulin, Insulin) was fixed.
ISSN:1063-777X
1090-6517
DOI:10.1063/10.0009736