New triterpene and antibacterial labdenoic acid derivatives from Moldenhawera nutans

A new triterpene derivative (22beta-hydroxylupeol) was isolated from the MeOH extract of stems of Moldenhawera nutans (Leguminosae) together with labdenoic acid derivatives of common occurrence in this species. From the labd-8(17)-en-15-oic acid were prepared simple derivatives, which exhibited in v...

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Bibliographic Details
Published in:Journal of the Brazilian Chemical Society 2007, Vol.18 (8), p.1585-1589
Main Authors: David, Juceni P., Ferrari, Jailton, David, Jorge M., Guimarães, Alaíse G., Lima, Fernanda W. de M., Souza, Geórgia L. S. de
Format: Article
Language:eng ; por
Subjects:
CHEMISTRY, MULTIDISCIPLINARY
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Summary:A new triterpene derivative (22beta-hydroxylupeol) was isolated from the MeOH extract of stems of Moldenhawera nutans (Leguminosae) together with labdenoic acid derivatives of common occurrence in this species. From the labd-8(17)-en-15-oic acid were prepared simple derivatives, which exhibited in vitro weak activity against Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Salmonella cholerasuis, and Vibrio parahaemolyticus.
ISSN:0103-5053
1678-4790
DOI:10.1590/S0103-50532007000800022