Long-Term Mortality in Cardioinhibitory Carotid Sinus Hypersensitivity Patient Cohort

Cardioinhibitory carotid sinus hypersensitivity (CICSH) is defined as ventricular asystole ≥ 3 seconds in response to 5-10 seconds of carotid sinus massage (CSM). There is a common concern that a prolonged asystole episode could lead to death directly from bradycardia or as a consequence of serious...

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Bibliographic Details
Published in:Arquivos brasileiros de cardiologia 2020-02, Vol.114 (2), p.245-253
Main Authors: Lacerda, Gustavo de Castro, Lorenzo, Andrea Rocha de, Tura, Bernardo Rangel, Santos, Marcela Cedenilla Dos, Guimarães, Artur Eduardo Cotrim, Lacerda, Renato Côrtes de, Pedrosa, Roberto Coury
Format: Article
Language:eng ; por
Subjects:
Aged
Bradycardia
CARDIAC & CARDIOVASCULAR SYSTEMS
Cardiac Pacing, Artificial
Carotid Artery Diseases - mortality
Carotid Artery Diseases - physiopathology
Carotid Sinus - physiopathology
Carotid Sinus,Massage/mortality
Electrocardiography
Female
Follow-Up Studies
Heart Arrest - mortality
Heart Arrest - physiopathology
Heart Injuries - mortality
Heart Injuries - physiopathology
Humans
Kaplan-Meier Estimate
Longitudinal Studies
Male
Middle Aged
Original
Proportional Hazards Models
Risk Factors
Statistics, Nonparametric
Syncope
Syncope - mortality
Syncope - physiopathology
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Summary:Cardioinhibitory carotid sinus hypersensitivity (CICSH) is defined as ventricular asystole ≥ 3 seconds in response to 5-10 seconds of carotid sinus massage (CSM). There is a common concern that a prolonged asystole episode could lead to death directly from bradycardia or as a consequence of serious trauma, brain injury or pause-dependent ventricular arrhythmias. To describe total mortality, cardiovascular mortality and trauma-related mortality of a cohort of CICSH patients, and to compare those mortalities with those found in a non-CICSH patient cohort. In 2006, 502 patients ≥ 50 years of age were submitted to CSM. Fifty-two patients (10,4%) were identified with CICSH. Survival of this cohort was compared with that of another cohort of 408 non-CICSH patients using Kaplan-Meier curves. Cox regression was used to examine the relation between CICSH and mortality. The level of statistical significance was set at 0.05. After a maximum follow-up of 11.6 years, 29 of the 52 CICSH patients (55.8%) were dead. Cardiovascular mortality, trauma-related mortality and the total mortality rate of this population were not statistically different from that found in 408 patients without CICSH. (Total mortality of CICSH patients 55.8% vs. 49,3% of non-CICSH patients; p: 0.38). At the end of follow-up, the 52 CICSH patient cohort had total mortality, cardiovascular mortality and trauma-related mortality similar to that found in 408 patients without CICSH.
ISSN:0066-782X
1678-4170
1678-4170
DOI:10.36660/abc.20190008