A naphthalene diimide dyad for fluorescence switch-on detection of G-quadruplexesElectronic supplementary information (ESI) available. See DOI: 10.1039/c5cc01536g

A non-fluorescent naphthalene diimide (NDI) dimer, conjugating red and blue NDI dyes, becomes red/NIR emitting upon G-quadruplex binding. The fluorescence lifetime which is significantly different for the complexes, the G-quadruplex/dimer and the weakly emitting ds-DNA/dimer is the key feature for t...

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Bibliographic Details
Main Authors: Doria, F, Oppi, A, Manoli, F, Botti, S, Kandoth, N, Grande, V, Manet, I, Freccero, M
Format: Article
Language:English
Online Access:Get full text
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Summary:A non-fluorescent naphthalene diimide (NDI) dimer, conjugating red and blue NDI dyes, becomes red/NIR emitting upon G-quadruplex binding. The fluorescence lifetime which is significantly different for the complexes, the G-quadruplex/dimer and the weakly emitting ds-DNA/dimer is the key feature for the development of new rationally engineered G-quadruplex sensors. A non-fluorescent dimeric naphthalene diimide dye becomes red emitting upon G-quadruplex binding.
ISSN:1359-7345
1364-548X
DOI:10.1039/c5cc01536g