Monitoring phases and phase transitions in phosphatidylethanolamine monolayers using active interfacial microrheologyElectronic supplementary information (ESI) available. See DOI: 10.1039/c4sm02900c

Active interfacial microrheology is a sensitive tool to detect phase transitions and headgroup order in phospholipid monolayers. The re-orientation of a magnetic nickel nanorod is used to explore changes in the surface rheology of 1,2-dilauroyl- sn -glycero-3-phosphoethanolamine (DLPE) and 1,2-dimyr...

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Main Authors: Ghazvini, Saba, Ricke, Brandon, Zasadzinski, Joseph A, Dhar, Prajnaparamita
Format: Article
Language:English
Online Access:Get full text
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Summary:Active interfacial microrheology is a sensitive tool to detect phase transitions and headgroup order in phospholipid monolayers. The re-orientation of a magnetic nickel nanorod is used to explore changes in the surface rheology of 1,2-dilauroyl- sn -glycero-3-phosphoethanolamine (DLPE) and 1,2-dimyristoyl- sn -glycero-3-phosphoethanolamine (DMPE), which differ by two CH 2 groups in their alkyl chains. Phosphatidylethanolamines such as DLPE and DMPE are a major component of cell membranes in bacteria and in the nervous system. At room temperature, DLPE has a liquid expanded (LE) phase for surface pressure, Π < ∼38 mN m −1 ; DMPE has an LE phase for Π < ∼7 mN m −1 . In their respective LE phases, DLPE and DMPE show no measurable change in surface viscosity with Π , consistent with a surface viscosity
ISSN:1744-683X
1744-6848
DOI:10.1039/c4sm02900c