Facile preparation of amine and amino acid adducts of [60]fullerene using chlorofullerene C60Cl6 as a precursorElectronic supplementary information (ESI) available: General experimental procedures for 1a-k, HPLC profiles, NMR and UV-Vis spectra for 1a-k; selected crystallographic data for 1d. CCDC 861958. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c2cc00071g

We report a general synthetic approach to the preparation of highly functionalized amine and amino acid derivatives of [60]fullerene starting from readily available chlorofullerene C 60 Cl 6 . The synthesized water-soluble amino acid derivative of C 60 demonstrated pronounced antiviral activity, whi...

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Main Authors: Kornev, Alexey B, Khakina, Ekaterina A, Troyanov, Sergey I, Kushch, Alla A, Peregudov, Alexander, Vasilchenko, Alexey, Deryabin, Dmitry G, Martynenko, Vyacheslav M, Troshin, Pavel A
Format: Article
Language:English
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Summary:We report a general synthetic approach to the preparation of highly functionalized amine and amino acid derivatives of [60]fullerene starting from readily available chlorofullerene C 60 Cl 6 . The synthesized water-soluble amino acid derivative of C 60 demonstrated pronounced antiviral activity, while the cationic amine-based compound showed strong antibacterial action in vitro. A novel approach to the highly selective synthesis of amine and amino acid derivatives of [60]fullerene has been developed.
ISSN:1359-7345
1364-548X
DOI:10.1039/c2cc00071g