Towards preparative-scale, biocatalytic alkene reductionsThis article is part of the 'Enzymes and Proteins' web-theme issue for ChemComm.Electronic supplementary information (ESI) available: Details of substrate and enzyme protocols. See DOI: 10.1039/c0cc03119d

Simple strategies for using alkene reductase enzymes to produce gram-scale quantities of both ( R )- and ( S )-citronellal have been developed. The methodology is easily accessible to non-specialist laboratories, allowing alkene reductases to be added to the toolbox of routine synthetic transformati...

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Main Authors: Bougioukou, Despina J, Walton, Adam Z, Stewart, Jon D
Format: Article
Language:English
Online Access:Get full text
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Summary:Simple strategies for using alkene reductase enzymes to produce gram-scale quantities of both ( R )- and ( S )-citronellal have been developed. The methodology is easily accessible to non-specialist laboratories, allowing alkene reductases to be added to the toolbox of routine synthetic transformations. Reaction strategies for employing two complementary alkene reductase enzymes in laboratory-scale conversions have been developed.
ISSN:1359-7345
1364-548X
DOI:10.1039/c0cc03119d