Acceptability, Feasibility, and Validity of Detecting Respiratory Pathogens During Acute Respiratory Illness in Participant-Collected Swabs in a Low-Income, Community Sample

Abstract Background Community surveillance for acute respiratory illness (ARI) can include unsupervised participant-collected nasal swabs. Little is known about use of self-swabs in low-income populations or among households including extended family members and the validity of self-collected swabs....

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Bibliographic Details
Published in:Open forum infectious diseases 2023-03, Vol.10 (3), p.ofad068-ofad068
Main Authors: Thind, Priyam, Vargas, Celibell Y, Reed, Carrie, Wang, Liqun, Alba, Luis R, Larson, Elaine L, Saiman, Lisa, Stockwell, Melissa S
Format: Article
Language:English
Subjects:
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Households
Influenza
Major
Medical research
Medicine, Experimental
Pathogenic microorganisms
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Summary:Abstract Background Community surveillance for acute respiratory illness (ARI) can include unsupervised participant-collected nasal swabs. Little is known about use of self-swabs in low-income populations or among households including extended family members and the validity of self-collected swabs. We assessed the acceptability, feasibility, and validity of unsupervised participant-collected nasal swabs in a low-income, community sample. Methods This was a substudy of a larger prospective community-based ARI surveillance study in 405 households in New York City. Participating household members self-collected swabs on the day of a research home visit for an index case, and for 3–6 subsequent days. Demographics associated with agreement to participate and swab collection were assessed, and index case self-collected versus research staff–collected swab results were compared. Results Most households (n = 292 [89.6%]) agreed to participate, including 1310 members. Being
ISSN:2328-8957
2328-8957
DOI:10.1093/ofid/ofad068