Medication‐resistant acute focal motor seizures in a child with COVID‐19 affecting the CNS

A perfectly healthy preschool girl presented with acute repetitive focal aware motor seizures, while her brain MRI showed a lesion in the left posterior cortex. After a number of investigations, her cerebrospinal fluid PCR was positive for SARS‐CoV‐2. Despite receiving at least four anti‐seizure med...

Full description

Saved in:
Bibliographic Details
Published in:Epileptic disorders 2022-10, Vol.24 (5), p.941-946
Main Authors: Sadeghian, Saeid, Momen, Aliakbar, Jelodar, Gholamreza, Nasiri, Shahram, Azizimalamiri, Reza
Format: Article
Language:English
Subjects:
Cerebrospinal fluid
Child
Child, Preschool
children
Clinical Commentaries
COVID-19
COVID-19 - complications
Epilepsy, Partial, Motor
Female
focal seizures
Humans
Immunoglobulins, Intravenous - therapeutic use
Inflammation
Intravenous administration
SARS-CoV-2
Seizures
Seizures - drug therapy
Seizures - etiology
Severe acute respiratory syndrome coronavirus 2
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A perfectly healthy preschool girl presented with acute repetitive focal aware motor seizures, while her brain MRI showed a lesion in the left posterior cortex. After a number of investigations, her cerebrospinal fluid PCR was positive for SARS‐CoV‐2. Despite receiving at least four anti‐seizure medications at appropriate dosages, the seizures continued, and just after administering intravenous immunoglobulin, her seizures stopped. This dramatic response to intravenous immunoglobulin may indicate a hypothetical inflammatory process in the patient’s cortex caused by COVID‐19.
ISSN:1294-9361
1950-6945
DOI:10.1684/epd.2022.1461