Etiologies, Gross Appearance, Histopathological Patterns, Prognosis, and Best Treatments for Subtypes of Renal Carcinoma: An Educational Review

Of all primary renal neoplasms, 80-85% are renal cell carcinomas (RCCs), which develop in the renal cortex. There are more than 10 histological and molecular subtypes of the disease, the most frequent of which is clear cell RCC, which also causes most cancer-related deaths. Other renal neoplasms, in...

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Published in:Curēus (Palo Alto, CA) CA), 2022-12, Vol.14 (12), p.e32338
Main Authors: Mohd, Ahmed B, Ghannam, Reem A, Mohd, Omar B, Elayan, Rama, Albakri, Khaled, Huneiti, Nesreen, Daraghmeh, Farah, Al-Khatatbeh, Eman, Al-Thnaibat, Mohammad
Format: Article
Language:English
Subjects:
Bladder cancer
Cancer therapies
Chromosomes
Cytoplasm
Etiology
Genes
Hypertension
Internal Medicine
Kidney cancer
Medical prognosis
Metastasis
Mutation
Nephrology
Oncology
Patients
Sarcoma
Tumors
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Summary:Of all primary renal neoplasms, 80-85% are renal cell carcinomas (RCCs), which develop in the renal cortex. There are more than 10 histological and molecular subtypes of the disease, the most frequent of which is clear cell RCC, which also causes most cancer-related deaths. Other renal neoplasms, including urothelial carcinoma, Wilms' tumor, and renal sarcoma, each affect a particular age group and have specific gross and histological features. Due to the genetic susceptibility of each of these malignancies, early mutation discovery is necessary for the early detection of a tumor. Furthermore, it is crucial to avoid environmental factors leading to each type. This study provides relatively detailed and essential information regarding each subtype of renal carcinoma.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.32338