PrEdictive value of coMbined pre-test proBability and blOod gas anaLysis In pulmonary emboliSM—the EMBOLISM study

In patients with suspected pulmonary embolism (PE), the number of unnecessary computed tomography pulmonary angiography (CTPA) scans remains high, especially in patients with low pre-test probability (PTP). So far, no study showed any additional benefit of capillary blood gas analysis (BGA) in diagn...

Full description

Saved in:
Bibliographic Details
Published in:Internal and emergency medicine 2022-11, Vol.17 (8), p.2245-2252
Main Authors: Meusel, Moritz, Pätz, Toni, Gruber, Kim, Kupp, Sebastian, Jensch, Philipp-Johannes, Saraei, Roza, Fürschke, Alexander, Sayk, Friedhelm, Eitel, Ingo, Wolfrum, Sebastian
Format: Article
Language:English
Subjects:
Algorithms
Angiography
Blood Gas Analysis
Computed tomography
Embolism
Fibrin Fibrinogen Degradation Products - analysis
Humans
Im - Original
Internal Medicine
Medicine
Medicine & Public Health
Oxygen
Patients
Predictive Value of Tests
Probability
Pulmonary Embolism - diagnosis
Pulmonary embolisms
Retrospective Studies
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In patients with suspected pulmonary embolism (PE), the number of unnecessary computed tomography pulmonary angiography (CTPA) scans remains high, especially in patients with low pre-test probability (PTP). So far, no study showed any additional benefit of capillary blood gas analysis (BGA) in diagnostic algorithms for PE. In this retrospective analysis of patients with suspected PE and subsequent CTPA, clinical data, D-dimer levels and BGA parameters (including standardized PaO2) were analyzed. Logistic regression analyses were performed to identify independent predictors for PE and reduce unnecessary CTPA examinations in patients with low PTP according to Wells score. Of 1538 patients, PE was diagnosed in 433 patients (28.2%). The original Wells score (odds ratio: 1.381 [95% CI 1.300–1.467], p  
ISSN:1828-0447
1970-9366
DOI:10.1007/s11739-022-03075-w