ODP217 Is Major Depressive Disorder in DKA Associated with Worse Patient Outcomes? A National Readmission Database Analysis

Abstract Introduction Major depressive disorder (MDD) is highly prevalent inpatientswith Diabetes type 1 (DM1),its impact on DKA incidence and outcomes is not well documented. Our goal with this study isto outline the impact of MDD on patients admitted with DKA and compare outcomes with those withou...

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Published in:Journal of the Endocrine Society 2022-11, Vol.6 (Supplement_1), p.A323-A323
Main Authors: Ramirez, Marcelo, Shaka, Hafeez, Sandino, Gabriela, Aguilera, Maria
Format: Article
Language:English
Subjects:
Diabetes & Glucose Metabolism
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Summary:Abstract Introduction Major depressive disorder (MDD) is highly prevalent inpatientswith Diabetes type 1 (DM1),its impact on DKA incidence and outcomes is not well documented. Our goal with this study isto outline the impact of MDD on patients admitted with DKA and compare outcomes with those without comorbid MDD. Methods This was a retrospective study involving adult hospitalizations for DKA in patients with T1D in the USA. We extracted data from the Nationwide Readmissions Database (NRD) of 2018. The study involved hospitalizations with DKA as the principal diagnosis in patients with T1D using ICD-10 diagnostic codes (E101). We deemed this as the reason for the index admission. This cohort was grouped based on the presence of a secondary diagnostic code of depressive disorder. Using unique hospitalization identifiers available in the NRD, we identified index hospitalizations, and one subsequent hospitalization within 30 days was tagged as readmission. Outcomes included comparing the 30-day all cause readmission of DKA in patients with and without depressive disorders. We also compared DKA specific readmission in both groups. We compared mortality, mean length of hospital stay (LOS), total hospital charges (THC), and cost of hospitalization (COH) between the groups. We also assessed whether comorbid depressive disorder is an independent predictor for readmission in hospitalizations for DKA. Results Of 94,747 patients admitted with DKA, 17.93% had a diagnosis of major depression disorder (MDD). Mean length of hospitalization during initial admission was longer in patients with MDD by 0.5 days in comparison to those without (3.35 vs. 2.84 days; p
ISSN:2472-1972
2472-1972
DOI:10.1210/jendso/bvac150.669