Assessment of the Relationship Between CD34 Antigen and Vitamin D Level and Insulin Resistance in Patients With Type 2 Diabetes

Diabetes causes disorders in the performance of endothelial progenitor cells, and obesity and vitamin D deficiency are associated with endothelial dysfunction and cardiovascular disease. This case-control study investigated the relationship between serum CD34 antigen and vitamin D levels and insulin...

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Bibliographic Details
Published in:Clinical diabetes 2022-01, Vol.40 (4), p.425-433
Main Authors: Pouresmaeil, Vahid, Ebre, Shaker, Yazdi, Mohammad Sarafraz
Format: Article
Language:English
Subjects:
Antigens
Diabetes
Glucose
Insulin resistance
Vitamin D
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Summary:Diabetes causes disorders in the performance of endothelial progenitor cells, and obesity and vitamin D deficiency are associated with endothelial dysfunction and cardiovascular disease. This case-control study investigated the relationship between serum CD34 antigen and vitamin D levels and insulin resistance in type 2 diabetes. The results showed that CD34 has a significant inverse relationship with BMI, A1C, fasting blood glucose, insulin resistance, and insulin levels and has a significant direct relationship with vitamin D levels. Both CD34 and vitamin D were found to be significantly associated with type 2 diabetes. The association between reduced CD34 and vitamin D levels with type 2 diabetes and increased insulin resistance suggests that these parameters may be helpful in assessing diabetes and predicting its complications.
ISSN:0891-8929
1945-4953
DOI:10.2337/cd21-0091