Al-hijamah (the triple S treatment of prophetic medicine) significantly increases CD4/CD8 ratio in thalassemic patients via increasing TAC/MDA ratio: a clinical trial

Beta thalassemia is associated with decreased immunity possibly due to iron overload. Al-hijamah (Hijamah) is wet cupping therapy (WCT) of prophetic medicine. Prophet Muhammad Peace be upon him said: “The best among your treatments is Al-hijamah”. Al-hijamah is a promising excretory treatment to cle...

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Published in:American journal of blood research 2022-08, Vol.12 (4), p.125-135
Main Authors: El-Shanshory, Mohamed, Hablas, Nahed Mohammed, El-Tahlawi, Rehab, Awny, Shereen, Aboonq, Moutasem Salih, Al Jaouni, Soad K, Abdel-Latif, Tamer Mohamed, Abdel-Gawad, Abdelhady Ragab, Okashah, Ahmed M, Fakhreldin, Ahmed R, Baghdadi, Hussam, El-Allaf, Hassan, Shebel, Yasmin, El-Sawy, Samer A, Albeihany, Amal, Mahmoud, Hany Salah, Sayed, Anwar A, Abu-Elnaga, Mostafa Am, Nabo, Manal Mohamed Helmy, El-Dardear, Amr, Abdel-Rahman, Ibrahim M, El Sayed, Salah Mohamed, Mahmoud, Ahmed Alamir
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Language:English
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Summary:Beta thalassemia is associated with decreased immunity possibly due to iron overload. Al-hijamah (Hijamah) is wet cupping therapy (WCT) of prophetic medicine. Prophet Muhammad Peace be upon him said: “The best among your treatments is Al-hijamah”. Al-hijamah is a promising excretory treatment to clear blood of causative pathological substances. Al-hijamah is a three-step technique (skin suction, scarification and suction) i.e. triple S technique). Recently, we introduced Al-hijamah as a novel iron excretion therapy (through pressure-dependent filtration then excretion via the skin dermal capillaries) that significantly decreased serum iron overload and related oxidative stress using a physiological excretory mechanism (Taibah mechanism). Iron overload was reported to impair both humoral immunity and cell mediated immunity in patients with beta thalassemia. In this study, twenty patients having β-thalassemia major (maintained on iron chelation therapy) underwent a single session of Al-hijamah (30-60 minutes) using 4-5 sucking cups only. Another age and sex-matched control group of thalassemic patients received iron chelation therapy only. Al-hijamah enhanced the immunity of thalassemic patients in the form of increased CD4 + T cell count, from 124.10±36.98 to 326.20±57.94 cells/mm 3 , and an increased CD8 + T cell count from 100.30±36.98 to 272.40±46.37 cells/mm 3 . CD4/CD8 ratio significantly increased from 1.29 to 1.7 (P
ISSN:2160-1992
2160-1992