Outcomes of radical cystectomy in pT4 bladder cancer frail patients: Α high-volume single center study

ObjectivesThis study aims to evaluate the effect of frailty in patients undergoing radical cystectomy (RC) for locally advanced bladder cancer. MethodsIn this retrospective, single center study we evaluated 51 patients with pT4 bladder cancer treated with radical cystectomy between 2016-2020. Patien...

Full description

Saved in:
Bibliographic Details
Published in:Journal of frailty, sarcopenia and falls sarcopenia and falls, 2022-09, Vol.7 (3), p.147-150
Main Authors: Stamatakos, Panagiotis Velissarios, Moschotzopoulos, Dimitrios, Glykas, Ioannis, Fragkoulis, Charalampos, Kostakopoulos, Nikolaos, Papadopoulos, Georgios, Stathouros, Georgios, Aristas, Odysseas, Dellis, Athanasios, Papatsoris, Athanasios, Ntoumas, Konstantinos
Format: Article
Language:English
Subjects:
Original
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:ObjectivesThis study aims to evaluate the effect of frailty in patients undergoing radical cystectomy (RC) for locally advanced bladder cancer. MethodsIn this retrospective, single center study we evaluated 51 patients with pT4 bladder cancer treated with radical cystectomy between 2016-2020. Patient frailty was assessed with the Clinical Frailty Scale (CFS). Furthermore, six separate parameters (early mortality index within 30 days after surgery, death after one year, length of stay, respiratory complications, readmission index, total hospital charges) were also evaluated. The patients were categorized on three groups (Group 1, 2, 3) based on the CFS. ResultsA total of 51 pT4 RC patients were included in the study. Mean age was 75.6 years. Early mortality rate at 30 days after surgery was low all the groups. One year mortality rate was higher in Group 2 (22%) and 3 (69%). The length of stay and the number of patients with respiratory complications were also higher in the frailer groups. 30 days readmission rate was 22% in Group 2 and 38% in Group 3. ConclusionsPreoperative frailty is associated with worse postoperative results after RC. CFS is an objective tool for patient risk stratification and can predict postoperative complications and mortality.
ISSN:2459-4148
2459-4148
DOI:10.22540/JFSF-07-147