Positive Outcomes: Validity, reliability and responsiveness of a novel person‐centred outcome measure for people with HIV

Objectives Despite successful treatment, people living with HIV experience persisting and burdensome multidimensional problems. We aimed to assess the validity, reliability and responsiveness of Positive Outcomes, a patient‐reported outcome measure for use in clinical practice. Methods In all, 1392...

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Published in:HIV medicine 2022-07, Vol.23 (6), p.673-683
Main Authors: Harding, Richard, Jones, Christopher Iain, Bremner, Stephen, Bristowe, Katherine, West, Brian, Siegert, Richard J., O’Brien, Kelly K., Whetham, Jennifer, Whetham, J., Fatz, D., Weir, G., Borges, M., Teofilo, E., Rodrigues, G., Cunha, A., Fisher, C., Beaumont, S., West, B., Dutarte, M., von Lingen, A. I., Greenhalgh, F., Block, K., Garcia, F., Garcia, D., Muñoz Pina, R., Etcheverry, F., Leal, L., Moreno, L., González, E., Apers, L., Mertens, L., Hoornaert, S., Begovac, J., Zekan, S., Benkovic, I., Wyatt, J., Fraser, M., Beck, E., Mandalia, S., Yfantopoulos, P., Gomez, E.J., Chausa, P., Gárate, F.J., Henwood, F., Darking, M., Marent, B., Bremner, S., Jones, C., Cáceres, C., Harding, R., León, A., Wallitt, E.
Format: Article
Language:English
Subjects:
Consistency
Convergence
Empowerment
Frailty
HIV
HIV Infections
Human immunodeficiency virus
Humans
measurement
Original Research
Outcome Assessment, Health Care
outcomes
Patients
person‐centredness
Psychometrics - methods
Quality of Life
Reliability analysis
Reliability aspects
Reproducibility of Results
Self report
Sexually transmitted diseases
STD
Surveys and Questionnaires
Validity
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Summary:Objectives Despite successful treatment, people living with HIV experience persisting and burdensome multidimensional problems. We aimed to assess the validity, reliability and responsiveness of Positive Outcomes, a patient‐reported outcome measure for use in clinical practice. Methods In all, 1392 outpatients in five European countries self‐completed Positive Outcomes, PAM‐13 (patient empowerment), PROQOL‐HIV (quality of life) and FRAIL (frailty) at baseline and 12 months. Analysis assessed: (a) validity (structural, convergent and divergent, discriminant); (b) reliability (internal consistency, test‐retest); and (c) responsiveness. Results An interpretable four‐factor structure was identified: ‘emotional wellbeing’, ‘interpersonal and sexual wellbeing’, ‘socioeconomic wellbeing’ and ‘physical wellbeing’. Moderate to strong convergent validity was found for three subscales of Positive Outcomes and PROQOL (ρ = −0.481 to −0.618, all p 
ISSN:1464-2662
1468-1293
DOI:10.1111/hiv.13224