The predictive value of modified risk scores in patients with acute exacerbation of COPD: a retrospective cohort study

This study aims to evaluate the performance of CREWS (Chronic Respiratory Early Warning Score), S-NEWS (Salford-National Early Warning Score), qNEWS (Quick National Early Warning Score), NEWS (National Early Warning Score), and qSOFA (Quick Sequential Organ Failure Assessment) scores in predicting m...

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Bibliographic Details
Published in:Internal and emergency medicine 2022-10, Vol.17 (7), p.2119-2127
Main Authors: İlhan, Buğra, Bozdereli Berikol, Göksu, Doğan, Halil
Format: Article
Language:English
Subjects:
Chronic obstructive pulmonary disease
Cohort analysis
Creatinine
EM - Original
Emergency medical care
Hospital Mortality
Humans
Intensive Care Units
Internal Medicine
Lung diseases
Mechanical ventilation
Medicine
Medicine & Public Health
Mortality
Obstructive lung disease
Patients
Performance evaluation
Prognosis
Pulmonary Disease, Chronic Obstructive - complications
Retrospective Studies
Risk Factors
ROC Curve
Sepsis - complications
Vital signs
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Summary:This study aims to evaluate the performance of CREWS (Chronic Respiratory Early Warning Score), S-NEWS (Salford-National Early Warning Score), qNEWS (Quick National Early Warning Score), NEWS (National Early Warning Score), and qSOFA (Quick Sequential Organ Failure Assessment) scores in predicting mortality, intensive care unit (ICU) admission and the need for mechanical ventilation (MV) of patients presented with acute exacerbations of chronic obstructive pulmonary disease (AECOPD). This retrospective cohort study was conducted in the emergency department of a tertiary hospital between January 1 and December 31, 2019. The patients with AECOPD and aged ≥ 18 were included. Patients who were transferred from another center and whose data could not be reached were excluded. Demographic information, comorbid diseases, variables of the scores, laboratory results, and outcomes were recorded. A total of 575 consecutive patients were included. The 30-day mortality, ICU admission, and MV need rate were 5.7% ( n  = 33), 9.6% ( n  = 55), and 13.7% ( n  = 79), respectively. Each score had moderate-to-excellent performance in predicting MV need and ICU admission, while their performance in predicting mortality was poor. CREWS is the most successful score in predicting 30-day mortality (AUC 0.695), ICU admission (AUC 0.841), and MV need (AUC 0.924). ICU admission, age, and creatinine levels were associated with mortality ( p  
ISSN:1828-0447
1970-9366
1970-9366
DOI:10.1007/s11739-022-03048-z