Mid-term pulmonary sequelae after hospitalisation for COVID-19: the French SISCOVID cohort

Even though COVID-19 clinical features, pathogenesis, complications, and therapeutic options have been largely described in the literature, long-term consequences in patients remain poorly known. The French, multicentre, non-interventional SISCOVID study evaluated lung impairment three (M3) and six...

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Published in:Respiratory medicine and research 2022-11, Vol.82, p.100933-100933, Article 100933
Main Authors: Calcaianu, George, Degoul, Samuel, Michau, Bénédicte, Payen, Thibault, Gschwend, Anthony, Fore, Mathieu, Iamandi, Carmen, Morel, Hugues, Oster, Jean-Philippe, Bizieux, Acya, Nocent-Ejnaini, Cécilia, Carvallo, Cécile, Romanet, Stéphanie, Goupil, François, Leurs, Amélie, Legrand, Marie-Germaine, Portel, Laurent, Claustre, Johanna, Calcaianu, Mihaela, Bresson, Didier, Debieuvre, Didier
Format: Article
Language:English
Subjects:
COVID-19
observational study
Original
patient discharge
pneumonia
sequelae
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Summary:Even though COVID-19 clinical features, pathogenesis, complications, and therapeutic options have been largely described in the literature, long-term consequences in patients remain poorly known. The French, multicentre, non-interventional SISCOVID study evaluated lung impairment three (M3) and six months (M6) after hospital discharge in patients recovered from COVID-19. Evaluation was based on clinical examination, pulmonary function tests, and chest computed tomography (CT-scan). Of the 320 included patients (mean age: 61 years; men: 64.1%), 205 had had a severe form of COVID-19, being hospitalised in an intensive care unit (ICU), and requiring high flow nasal cannula, non-invasive ventilation, or invasive mechanical ventilation. At M6, 54.1% of included patients had persistent dyspnoea (mMRC score ≥1), 20.1% severe impairment in gas diffusing capacity (DLCO
ISSN:2590-0412
2590-0412
DOI:10.1016/j.resmer.2022.100933