Preferential carriage of class 2 integrons in Acinetobacter baumannii CC113 and novel singletons

Our understanding of the distribution of integrons associated with multidrug resistance in Acinetobacter baumannii isolates around the world remains incomplete. The association between the class 1 and 2 integron A. baumannii-positive isolates (n = 60), recovered since 1982 from 11 Argentinean hospit...

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Bibliographic Details
Published in:Epidemiology and infection 2015-10, Vol.143 (14), p.3118-3121
Main Authors: RAMÍREZ, M. S., MONTAÑA, S., CASSINI, M., CENTRÓN, D.
Format: Article
Language:English
Subjects:
Acinetobacter baumannii - classification
Acinetobacter baumannii - genetics
Acinetobacter baumannii - isolation & purification
Acinetobacter Infections - epidemiology
Acinetobacter Infections - microbiology
Argentina - epidemiology
Drug Resistance, Multiple, Bacterial
Genotype
Humans
Infections
Integrons
Molecular Epidemiology
SHORT REPORT
Zoonoses/Arboviral infections
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Summary:Our understanding of the distribution of integrons associated with multidrug resistance in Acinetobacter baumannii isolates around the world remains incomplete. The association between the class 1 and 2 integron A. baumannii-positive isolates (n = 60), recovered since 1982 from 11 Argentinean hospitals, and the circulating lineages, was investigated. While class 2 integrons were highly significantly associated with clonal lineage CC113B/CC79P (P = 0·009) and novel singletons (P = 0·001), class 1 integrons were found not to be associated with CC109B/CC1P or other lineages. The study reveals a differential distribution of class 2 integrons in lineages, and suggests that the prevalence of intI2 in Argentina is related to the emergence of novel singletons in recent years and to the abundance of CC113B/CC79P, which has been the local dominant lineage for several decades.
ISSN:0950-2688
1469-4409
DOI:10.1017/S0950268815000060