Transmission of SARS-CoV-2 within households: a remote prospective cohort study in European countries

Household transmission studies are useful to quantify SARS-CoV-2 transmission dynamics. We conducted a remote prospective household study to quantify transmission, and the effects of subject characteristics, household characteristics, and implemented infection control measures on transmission. House...

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Bibliographic Details
Published in:European journal of epidemiology 2022-05, Vol.37 (5), p.549-561
Main Authors: Verberk, Janneke D. M., de Hoog, Marieke L. A., Westerhof, Ilse, van Goethem, Sam, Lammens, Christine, Ieven, Greet, de Bruin, Erwin, Eggink, Dirk, Bielicki, Julia A., Coenen, Samuel, van Beek, Janko, Bonten, Marc J. M., Goossens, Herman, Bruijning-Verhagen, Patricia C. J. L.
Format: Article
Language:English
Subjects:
Antibodies
Cardiology
Cohort analysis
Covid-19
Diaries
Disease control
Epidemiology
Households
Infections
Infectious Diseases
Medicine
Medicine & Public Health
Oncology
Pandemics
Public Health
Sampling
Severe acute respiratory syndrome
Severe acute respiratory syndrome coronavirus 2
Viral diseases
Viruses
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Summary:Household transmission studies are useful to quantify SARS-CoV-2 transmission dynamics. We conducted a remote prospective household study to quantify transmission, and the effects of subject characteristics, household characteristics, and implemented infection control measures on transmission. Households with a laboratory-confirmed SARS-CoV-2 index case were enrolled  85% completed sample collection. 200 secondary SARS-CoV-2 infections were detected, yielding a household SAR of 45.7% (95% CI 39.7–51.7%) and per-person SAR of 32.6% (95%CI: 28.1-37.4%). 126 (63%) secondary cases were detected at enrollment. Mild (aRR = 0.57) and asymptomatic index cases (aRR = 0.29) were less likely to transmit SARS-CoV-2, compared to index cases with an acute respiratory illness ( p  = 0.03 for trend), and child index cases (
ISSN:0393-2990
1573-7284
DOI:10.1007/s10654-022-00870-9