Electrical status epilepticus during slow-wave sleep (ESES): Current perspectives

Electrical status epilepticus during slow-wave sleep (ESES) is an epilepsy syndrome with sleep-induced epileptic discharges and acquired impairment of cognition or behavior. Since the disease's original description in 1971, no clear consensus has emerged on diagnostic criteria or optimal treatm...

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Bibliographic Details
Published in:Journal of pediatric neurosciences 2021-04, Vol.16 (2), p.91-96
Main Authors: Arican, Pinar, Gencpinar, Pinar, Olgac Dundar, Nihal, Tekgul, Hasan
Format: Article
Language:English
Subjects:
Care and treatment
Homeopathy
Levetiracetam
Materia medica and therapeutics
Review
Sleep
Status epilepticus
Therapeutics
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Summary:Electrical status epilepticus during slow-wave sleep (ESES) is an epilepsy syndrome with sleep-induced epileptic discharges and acquired impairment of cognition or behavior. Since the disease's original description in 1971, no clear consensus has emerged on diagnostic criteria or optimal treatment. The treatment of ESES can be challenging, often including numerous antiepileptic drugs, immunomodulatory agents, and even surgical interventions. There is little evidence to guide treatment because only retrospective studies and case reports on the efficacy of treatment of ESES are present in literature. In this paper, we aim to analyze the etiopathogenesis of ESES in the new genetic era and to evaluate the treatment modalities in accordance with the genetic data and electroclinic spectrum of ESES.
ISSN:1817-1745
1998-3948
DOI:10.4103/jpn.JPN_137_20