An unusual onset of pediatric acute lymphoblastic leukemia

Acute lymphoblastic leukemia is the most frequent cancer in children: it represents 80% of leukemias and about 24% of all neoplasms diagnosed between 0 and 14 years. Acute lymphoblastic leukemia mainly affects children between 2 and 5 years old and in this age group the incidence is about 80–90 case...

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Bibliographic Details
Published in:Journal of ultrasound 2021-12, Vol.24 (4), p.555-560
Main Authors: Brillantino, Carmela, Rossi, Eugenio, Bifano, Delfina, Minelli, Rocco, Tamasi, Sonia, Mamone, Rosanna, Bignardi, Elio, Zeccolini, Raffaele, Zeccolini, Massimo, Vallone, Gianfranco
Format: Article
Language:English
Subjects:
Blood vessels
Bone marrow
Cancer
Case Report
Children
Leukemia
Medicine
Medicine & Public Health
Neoplasms
Ultrasound
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Summary:Acute lymphoblastic leukemia is the most frequent cancer in children: it represents 80% of leukemias and about 24% of all neoplasms diagnosed between 0 and 14 years. Acute lymphoblastic leukemia mainly affects children between 2 and 5 years old and in this age group the incidence is about 80–90 cases per million per year. In acute lymphoblastic leukemia, cancer cells multiply rapidly and accumulate in the bone marrow and subsequently invade the blood. However, at the time of diagnosis, leukemia rarely occurs outside the bone marrow or blood vessels and the extramedullary involvement happens mostly in patients with refractory or relapsing disease. In this article, we report an unusual clinical presentation of acute B cell lymphoblastic leukemia with intestinal and ovarian localizations in a 5-year-old girl.
ISSN:1876-7931
1971-3495
1876-7931
DOI:10.1007/s40477-020-00461-y