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Clinical profile of hospitalized COVID-19 patients in first & second wave of the pandemic: Insights from an Indian registry based observational study

Background & objectives: India witnessed a massive second surge of COVID-19 cases since March 2021 after a period of decline from September 2020. Data collected under the National Clinical Registry for COVID-19 (NCRC) were analysed to describe the differences in demographic and clinical features...

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Published in:Indian journal of medical research (New Delhi, India : 1994) India : 1994), 2021-05, Vol.153 (5), p.619-628
Main Authors: Kumar, Gunjan, Mukherjee, Aparna, Sharma, Ravendra, Menon, Geetha, Sahu, Damodar, Wig, Naveet, Panda, Samiran, Rao, Vishnu, Singh, Sujeet, Guleria, Randeep, Bhargava, Balram
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Language:English
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Summary:Background & objectives: India witnessed a massive second surge of COVID-19 cases since March 2021 after a period of decline from September 2020. Data collected under the National Clinical Registry for COVID-19 (NCRC) were analysed to describe the differences in demographic and clinical features of COVID-19 patients recruited during these two successive waves. Methods: The NCRC, launched in September 2020, is an ongoing multicentre observational initiative, which provided the platform for the current investigation. Demographic, clinical, treatment and outcome data of hospitalized, confirmed COVID-19 patients were captured in an electronic data portal from 41 hospitals across India. Patients enrolled during September 1, 2020 to January 31, 2021 and February 1 to May 11, 2021 constituted participants of the two successive waves, respectively. Results: As on May 11, 2021, 18961 individuals were recruited in the registry, 12059 and 6903 reflecting in-patients from the first and second waves, respectively. Mean age of the patients was significantly lower in the second wave [48.7 (18.1) yr vs. 50.7 (18.0) yr, P
ISSN:0971-5916
0975-9174
DOI:10.4103/ijmr.ijmr_1628_21