Severity of Disease Among Adults Hospitalized with Laboratory-Confirmed COVID-19 Before and During the Period of SARS-CoV-2 B.1.617.2 (Delta) Predominance — COVID-NET, 14 States, January–August 2021

What is already known about this topic? The SARS-CoV-2 B.1.617.2 (Delta) variant is highly transmissible; however, whether it causes more severe disease in adults has been uncertain. What is added by this report? Analysis of COVID-NET data from 14 states found no significant increases in the proport...

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Published in:MMWR. Morbidity and mortality weekly report 2021-10, Vol.70 (43), p.1513-1519
Main Authors: Taylor, Christopher A., Patel, Kadam, Pham, Huong, Whitaker, Michael, Anglin, Onika, Kambhampati, Anita K., Milucky, Jennifer, Chai, Shua J., Kirley, Pam Daily, Alden, Nisha B., Armistead, Isaac, Meek, James, Yousey-Hindes, Kimberly, Anderson, Evan J., Openo, Kyle P., Teno, Kenzie, Weigel, Andy, Monroe, Maya L., Ryan, Patricia A., Henderson, Justin, Nunez, Val Tellez, Bye, Erica, Lynfield, Ruth, Poblete, Mayvilynne, Smelser, Chad, Barney, Grant R., Spina, Nancy L., Bennett, Nancy M., Popham, Kevin, Billing, Laurie M., Shiltz, Eli, Abdullah, Nasreen, Sutton, Melissa, Schaffner, William, Talbot, H. Keipp, Ortega, Jake, Price, Andrea, Garg, Shikha, Havers, Fiona P., Roland, Jeremy, Blythe, David, Brooks, Alicia, Como-Sabetti, Kathryn, Danila, Richard, Judson, Melissa, Omondi, Wickliffe, Engesser, Kerianne, Rowe, Adam, Gaitán, Maria, Cafferky, Virginia, Freshwater, Julie, Salvator, Ann, Hawkins, Sam, Youngers, Emily, Markus, Tiffanie, Crossland, Melanie, McCaffrey, Keegan
Format: Article
Language:English
Subjects:
Adults
Age groups
Clinical outcomes
Coronaviruses
COVID-19
COVID-19 vaccines
Full Report
Hospitalization
Immunization
Medical laboratories
Older people
Public health
Severe acute respiratory syndrome coronavirus 2
Surveillance
Trends
Vaccination
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Summary:What is already known about this topic? The SARS-CoV-2 B.1.617.2 (Delta) variant is highly transmissible; however, whether it causes more severe disease in adults has been uncertain. What is added by this report? Analysis of COVID-NET data from 14 states found no significant increases in the proportion of hospitalized COVID-19 patients with severe outcomes during the Delta period. The proportion of hospitalized unvaccinated COVID-19 patients aged 18–49 years significantly increased during the Delta period. What are the implications for public health practice? Lower vaccination coverage in adults aged 18–49 years likely contributed to the increase in hospitalized patients during the Delta period. COVID-19 vaccination is critical for all eligible adults, including adults aged
ISSN:0149-2195
1545-861X
DOI:10.15585/mmwr.mm7043e1