Non-celiac gluten sensitivity as a rare cause of growth retardation in children: a case series study

Herein, we present five children and adolescents with a final diagnosis of non-celiac gluten sensitivity (NCGS). Non-celiac gluten sensitivity (NCGS) is a condition characterized by gastrointestinal and extra-intestinal symptoms triggered by ingestion of gluten-containing compounds, e.g., wheat, rye...

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Bibliographic Details
Published in:Gastroenterology and hepatology from bed to bench 2021-01, Vol.14 (4), p.362-366
Main Authors: Saneifard, Hedyeh, Sheikhy, Ali, Karbasian, Fereshteh, Eslamian, Golnaz, Shakiba, Marjan, Babaie, Delara
Format: Article
Language:English
Subjects:
Case Series
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Summary:Herein, we present five children and adolescents with a final diagnosis of non-celiac gluten sensitivity (NCGS). Non-celiac gluten sensitivity (NCGS) is a condition characterized by gastrointestinal and extra-intestinal symptoms triggered by ingestion of gluten-containing compounds, e.g., wheat, rye, and barley, in subjects without celiac disease or wheat allergy. Demographic characteristics, clinical manifestations, serum biomarkers and skin prick test were evaluated. Patient data was also recorded after they followed a gluten-free diet (GFD). Height and weight were measured, and all patients were examined 6 months after following the suggested GFD. All patients had failure to thrive and abdominal pain. Clinical symptoms were reduced, and significant weight and height gains were detected after 1 month of following a gluten-free diet. The relationship between failure to thrive (FTT) and NCGS is still unknown; hence, NCGS may be one of the main causes of FTT which can be prevented by gluten-free diets.
ISSN:2008-2258
2008-4234
DOI:10.22037/ghfbb.v14i4.2239