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Phlegmasia cerulea dolens superimposed on disseminated intravascular coagulation in COVID-19

COVID-19 infection has several cardiovascular implications, and coagulopathy is a common abnormality in these patients, often coupled with elevated plasma fibrinogen and D-dimer levels, contributing to adverse outcomes. Phlegmasia cerulea dolens (PCD) is a rare manifestation of deep vein thrombosis....

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Bibliographic Details
Published in:Acta bio-medica de l'Ateneo Parmense 2021-09, Vol.92 (4)
Main Authors: Orso, Daniele, Mattuzzi, Lisa, Scapol, Sara, Delrio, Silvia, Vetrugno, Luigi, Bove, Tiziana
Format: Article
Language:English
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Summary:COVID-19 infection has several cardiovascular implications, and coagulopathy is a common abnormality in these patients, often coupled with elevated plasma fibrinogen and D-dimer levels, contributing to adverse outcomes. Phlegmasia cerulea dolens (PCD) is a rare manifestation of deep vein thrombosis. It is life-threatening and can rapidly lead to venous gangrene of the extremity. Only a few cases of COVID-19 associated with PCD are reported in the literature, despite thromboembolism being the common paradigm between the two diseases. We present the case of a 64-year-old adult with acute severe COVID-19 pneumonia who developed PCD despite constantly elevated activated partial thromboplastin time and international normalized ratio. ( www.actabiomedica.it )
ISSN:0392-4203
2531-6745
DOI:10.23750/abm.v92i4.11478