Impact of vitamin D on the course of COVID-19 during pregnancy: A case control study

[Display omitted] •Pregnant COVID-19 patients tend to have lower vitamin D levels than healthy ones.•Healthy pregnant women are likely to have vitamin D deficiency and insufficiency.•Vitamin D deficiency may affect the course of COVID-19 in pregnant patients.•Vitamin D deficiency can be thought of a...

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Published in:The Journal of steroid biochemistry and molecular biology 2021-10, Vol.213, p.105964-105964, Article 105964
Main Authors: Sinaci, Selcan, Ocal, Doga Fatma, Yucel Yetiskin, Didem Fatma, Uyan Hendem, Derya, Buyuk, Gul Nihal, Goncu Ayhan, Sule, Tanacan, Atakan, Ozgu-Erdinc, A. Seval, Moraloglu Tekin, Ozlem, Sahin, Dilek
Format: Article
Language:English
Subjects:
Adult
Calcifediol - blood
Case-Control Studies
Coronaviruses
COVID-19
COVID-19 - blood
COVID-19 - diet therapy
COVID-19 - pathology
COVID-19 - virology
Cytokine Release Syndrome - blood
Cytokine Release Syndrome - diet therapy
Cytokine Release Syndrome - pathology
Cytokine Release Syndrome - virology
Cytokine storm
Dietary Supplements
Female
Gestational Age
Humans
Immune system
Pregnancy
Pregnancy Complications, Infectious - blood
Pregnancy Complications, Infectious - diet therapy
Pregnancy Complications, Infectious - pathology
Pregnancy Complications, Infectious - virology
SARS-CoV-2 - pathogenicity
Severe acute respiratory syndrome coronavirus 2
Severity of Illness Index
Statistical analysis
Treatment Outcome
Vitamin D
Vitamin D - administration & dosage
Vitamin D - analogs & derivatives
Vitamin D - blood
Vitamin D deficiency
Vitamin D Deficiency - blood
Vitamin D Deficiency - diet therapy
Vitamin D Deficiency - pathology
Vitamin D Deficiency - virology
Vitamin deficiency
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Summary:[Display omitted] •Pregnant COVID-19 patients tend to have lower vitamin D levels than healthy ones.•Healthy pregnant women are likely to have vitamin D deficiency and insufficiency.•Vitamin D deficiency may affect the course of COVID-19 in pregnant patients.•Vitamin D deficiency can be thought of as a risk factor for severe COVID-19. We aimed to evaluate the vitamin D status of pregnant women with COVID-19, and the association between vitamin D level and severity of COVID-19. In this case control study, 159 women with a single pregnancy and tested positive for SARS-CoV-2, and randomly selected 332 healthy pregnant women with similar gestational ages were included. COVID-19 patients were classified as mild, moderate, and severe. Vitamin D deficiency was defined as 25-hydroxycholecalciferol
ISSN:0960-0760
1879-1220
DOI:10.1016/j.jsbmb.2021.105964