A mouth rinse based on a tea solution of Salvia officinalis for oral discomfort in palliative cancer care: a randomized controlled trial

Background Few clinical studies evaluate interventions to reduce oral discomfort among patients in palliative care. Aim This study examines the efficacy of a Salvia officinalis (SO) based herbal mouth rinse compared to conventional normal saline (NS) in order to improve oral health. Design A block-r...

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Bibliographic Details
Published in:Supportive care in cancer 2021-09, Vol.29 (9), p.4997-5007
Main Authors: Monsen, Ragnhild Elisabeth, Herlofson, Bente Brokstad, Gay, Caryl, Fjeld, Katrine Gahre, Hove, Lene Hystad, Malterud, Karl Egil, Saghaug, Elisabeth, Slaaen, Joran, Sundal, Tone, Tollisen, Anita, Lerdal, Anners
Format: Article
Language:eng ; nor
Subjects:
Cancer
Cancer patients
Care and treatment
Clinical trials
Comparative analysis
Medical research
Medicine
Medicine & Public Health
Medicine, Experimental
Mouth
Nursing
Nursing Research
Oncology
Oral hygiene
Original
Original Article
Pain Medicine
Palliative care
Palliative treatment
Rehabilitation Medicine
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Summary:Background Few clinical studies evaluate interventions to reduce oral discomfort among patients in palliative care. Aim This study examines the efficacy of a Salvia officinalis (SO) based herbal mouth rinse compared to conventional normal saline (NS) in order to improve oral health. Design A block-randomized controlled trial. Data were collected before and after a 4-day intervention with either SO ( n =44) or NS ( n =44). Numerical rating scales (NRS, 0–10) and 12 items from the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire-Oral Health 17 (EORTC QLQ-OH17) measured patient-reported oral symptoms. An oral examination was performed before and after the intervention. Setting/participants This study included adult patients with late-stage cancer in an inpatient hospice unit. Results Of the 88 patients included (mean age=63.9 years, SD=10.6), 73 (83%) completed the study. At baseline, 78% reported dry mouth on the EORTC QLQ-OH17, and 80% rated dry mouth ≥4 on the NRS. Total oral health scores based on the 12 EORTC QLQ-OH17 items improved similarly in both groups ( p
ISSN:0941-4355
1433-7339
DOI:10.1007/s00520-021-06021-2