Undeclared Doping Substances are Highly Prevalent in Commercial Sports Nutrition Supplements

Sports nutrition supplements have previously been reported to contain undeclared doping substances. The use of such supplements can lead to general health risks and may give rise to unintentional doping violations in elite sports. To assess the prevalence of doping substances in a range of high-risk...

Full description

Saved in:
Bibliographic Details
Published in:Journal of sports science & medicine 2021-06, Vol.20 (2), p.328-338
Main Authors: Duiven, Erik, van Loon, Luc J C, Spruijt, Laila, Koert, Willem, de Hon, Olivier M
Format: Article
Language:English
Subjects:
Adrenergic beta-Agonists - analysis
Adrenergic beta-Antagonists - analysis
Alkaloids - analysis
Amphetamines - analysis
Androstadienes - analysis
Athletes
Chromatography
Dietary supplements
Dietary Supplements - analysis
Doping in Sports
Drug Contamination
Drug dosages
Drugs and athletes
Health aspects
Humans
Identification and classification
Illegal drugs
Laboratories
Mass spectrometry
Materials
Medical research
Medicine, Experimental
Nutrition
Prevalence
Product lines
Purchase orders
Regulation
Risk Assessment
Scientific imaging
Sports nutrition
Steroids
Testosterone Congeners - analysis
Tetrahydroisoquinolines - analysis
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Sports nutrition supplements have previously been reported to contain undeclared doping substances. The use of such supplements can lead to general health risks and may give rise to unintentional doping violations in elite sports. To assess the prevalence of doping substances in a range of high-risk sports nutrition supplements available from Dutch web shops. A total of 66 sports nutrition supplements - identified as potentially high-risk products claiming to modulate hormone regulation, stimulate muscle mass gain, increase fat loss, and/or boost energy - were selected from 21 different brands and purchased from 17 web shops. All products were analyzed for doping substances by the UK life sciences testing company LGC, formerly known as the Laboratory of the Government Chemist, using an extended version of their ISO17025 accredited nutritional supplement screen. A total of 25 out of the 66 products (38%) contained undeclared doping substances, which included high levels of the stimulants oxilofrine, β-methylphenethylamine (BMPEA) and N,β-dimethylphenethylamine (NBDMPEA), the stimulant 4-methylhexan-2-amine (methylhexaneamine, 1,3-dimethylamylamine, DMAA), the anabolic steroids boldione (1,4-androstadiene-3,17-dione) and 5-androstene-3β,17α-diol (17α-AED), the beta-2 agonist higenamine and the beta-blocker bisoprolol. Based upon the recommended dose and the potential variability of analyte concentration, the ingestion of some products identified within this study could pose a significant risk of unintentional doping violations. In addition to inadvertent doping risks, the prescribed use of 3 products (4.5%) could likely impose general health risks.
ISSN:1303-2968
1303-2968
DOI:10.52082/jssm.2021.328