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Effect of yoga on glycemia and lipid parameters in type-2 diabetes: a meta-analysis

Purpose Prior systematic reviews on yoga and diabetes have given conflicting results. They have been limited by inclusion of uncontrolled unblinded single group observational studies. No reviews are available which have used the Cochrane methodology and GRADE (Grades of Recommendation, Assessment, D...

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Published in:Journal of diabetes and metabolic disorders 2021-06, Vol.20 (1), p.349-367
Main Authors: Dutta, Deep, Bhattacharya, Saptarshi, Sharma, Meha, Khandelwal, Deepak, Surana, Vineet, Kalra, Sanjay
Format: Article
Language:English
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Summary:Purpose Prior systematic reviews on yoga and diabetes have given conflicting results. They have been limited by inclusion of uncontrolled unblinded single group observational studies. No reviews are available which have used the Cochrane methodology and GRADE (Grades of Recommendation, Assessment, Development and Evaluation) approach. This meta-analysis evaluated the efficacy of yoga on glycaemia and lipids in T2DM using the Cochrane methodology and GRADE approach. Methods Major repositories were searched to pick randomized controlled trials involving T2DM patients receiving yoga. Primary outcome was to evaluate changes in fasting plasma glucose (FPG) and glycated haemoglobin (HbA1c). Secondary outcomes were to evaluate changes in post-prandial plasma glucose (PPG), total cholesterol (TC), triglycerides, low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C). Sub-group analysis involving people undergoing structured exercise regimen (SER) versus those undergoing standard diabetes care in controls was done. Results Data from 13 studies involving 1440 patients were analysed. Compared to controls, individuals doing yoga had significantly lower FPG [mean difference (MD) -17.22 mg/dl (95% CI: −26.19 – −8.26 mg/dl); p  
ISSN:2251-6581
2251-6581
DOI:10.1007/s40200-021-00751-0