Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis Presenting with Diffusion MR Imaging Changes

Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT) presents with focal or diffuse nonenhancing MR imaging abnormalities in 50% of patients with SREAT during subacute exacerbation. Vasculitic changes in biopsy studies as well as the elevation of antithyroid antibodies an...

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Bibliographic Details
Published in:American journal of neuroradiology : AJNR 2008-09, Vol.29 (8), p.1550-1551
Main Authors: Grommes, C, Griffin, C, Downes, K.A, Lerner, A.J
Format: Article
Language:English
Subjects:
Adrenal Cortex Hormones - administration & dosage
Adult
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Anti-Inflammatory Agents - administration & dosage
Biological and medical sciences
Bone marrow, stem cells transplantation. Graft versus host reaction
Brain
Brain - pathology
Brain Diseases - complications
Brain Diseases - drug therapy
Brain Diseases - pathology
Diffusion Magnetic Resonance Imaging - methods
Female
Hashimoto Disease - complications
Hashimoto Disease - drug therapy
Hashimoto Disease - pathology
Humans
Investigative techniques, diagnostic techniques (general aspects)
Medical sciences
Nervous system
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Transfusions. Complications. Transfusion reactions. Cell and gene therapy
Treatment Outcome
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Summary:Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT) presents with focal or diffuse nonenhancing MR imaging abnormalities in 50% of patients with SREAT during subacute exacerbation. Vasculitic changes in biopsy studies as well as the elevation of antithyroid antibodies and CSF protein suggests an inflammatory cause. We report the case of a patient with SREAT with changes on diffusion-weighted MR imaging, which improved with corticosteroid therapy and plasmapheresis, supporting the theory of inflammatory changes in exacerbation of presumptive SREAT.
ISSN:0195-6108
1936-959X
DOI:10.3174/ajnr.A1113