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Genome Sequence of the Virulent Model Herpes Simplex Virus 1 Strain McKrae Demonstrates the Presence of at Least Two Widely Used Variant Strains

Herpes simplex virus 1 (HSV-1) strain McKrae was isolated in 1965 and has been utilized by many laboratories. Three HSV-1 strain McKrae stocks have been sequenced previously, revealing discrepancies in key genes. We sequenced the genome of HSV-1 strain McKrae from the laboratory of James M. Hill to...

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Bibliographic Details
Published in:Microbiology resource announcements 2021-03, Vol.10 (12)
Main Authors: Renner, Daniel W, Parsons, Lance, Shreve, Jacob T, Engel, Esteban A, Kuny, Chad V, Enquist, Lynn, Neumann, Donna, Mangold, Colleen, Szpara, Moriah L
Format: Article
Language:English
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Summary:Herpes simplex virus 1 (HSV-1) strain McKrae was isolated in 1965 and has been utilized by many laboratories. Three HSV-1 strain McKrae stocks have been sequenced previously, revealing discrepancies in key genes. We sequenced the genome of HSV-1 strain McKrae from the laboratory of James M. Hill to better understand the genetic differences between isolates.
ISSN:2576-098X
2576-098X
DOI:10.1128/mra.01146-19