Temozolomide (Temodar)

Temozolomide, an oral alkylating agent, is a commonly used medicine in the treatment of anaplastic astrocytoma and glioblastoma multiforme. This paper will present the mechanism of action as well as the clinical role for this chemotherapeutic drug.

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Bibliographic Details
Published in:American journal of neuroradiology : AJNR 2010-09, Vol.31 (8), p.1383-1384
Main Authors: WESOLOWSKI, J. R, RAJDEV, P, MUKHERJI, S. K
Format: Article
Language:English
Subjects:
Administration, Oral
Antineoplastic Agents, Alkylating - administration & dosage
Antineoplastic Agents, Alkylating - adverse effects
Antineoplastic Agents, Alkylating - economics
Astrocytoma - drug therapy
Biological and medical sciences
Brain Neoplasms - drug therapy
Dacarbazine - administration & dosage
Dacarbazine - adverse effects
Dacarbazine - analogs & derivatives
Dacarbazine - economics
Drug Costs
Glioblastoma - drug therapy
Humans
Investigative techniques, diagnostic techniques (general aspects)
Medical sciences
Nervous system
Pharmacology Vignette
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Temozolomide
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Description
Summary:Temozolomide, an oral alkylating agent, is a commonly used medicine in the treatment of anaplastic astrocytoma and glioblastoma multiforme. This paper will present the mechanism of action as well as the clinical role for this chemotherapeutic drug.
ISSN:0195-6108
1936-959X
DOI:10.3174/ajnr.A2170