Trastuzumab (Herceptin)

Herceptin (trastuzumab) is a human monoclonal antibody that interferes with the HER2 receptor. It is currently the only FDA-approved therapeutic antibody for HER2-positive breast cancer. This article will present the mechanism at action as well as the clinical role at this monoclonal antibody.

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Bibliographic Details
Published in:American journal of neuroradiology : AJNR 2011-09, Vol.32 (8), p.1373-1374
Main Authors: GEMMETE, J. J, MUKHERJI, S. K
Format: Article
Language:English
Subjects:
Antibodies, Monoclonal, Humanized - therapeutic use
Antineoplastic Agents - therapeutic use
Biological and medical sciences
Breast Neoplasms - drug therapy
Female
Humans
Investigative techniques, diagnostic techniques (general aspects)
Medical sciences
Nervous system
Pharmacology Vignette
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Trastuzumab
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Description
Summary:Herceptin (trastuzumab) is a human monoclonal antibody that interferes with the HER2 receptor. It is currently the only FDA-approved therapeutic antibody for HER2-positive breast cancer. This article will present the mechanism at action as well as the clinical role at this monoclonal antibody.
ISSN:0195-6108
1936-959X
DOI:10.3174/ajnr.A2619