Prognostic value of aerobic capacity and exercise oxygen pulse in postaortic dissection patients

Background Although recommendations encourage daily moderate activities in post aortic dissection, very little data exists regarding cardiopulmonary exercise testing (CPET) to personalize those patient's physical rehabilitation and assess their cardiovascular prognosis. Design We aimed at testi...

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Published in:Clinical cardiology (Mahwah, N.J.) N.J.), 2021-02, Vol.44 (2), p.252-260
Main Authors: Delsart, Pascal, Delahaye, Camille, Devos, Patrick, Domanski, Olivia, Azzaoui, Richard, Sobocinski, Jonathan, Juthier, Francis, Vincentelli, Andre, Rousse, Natacha, Mugnier, Agnes, Soquet, Jerome, Loobuyck, Valentin, Koussa, Mohamed, Modine, Thomas, Jegou, Bruno, Bical, Antoine, Hysi, Ilir, Fabre, Olivier, Pontana, François, Matran, Regis, Mounier‐Vehier, Claire, Montaigne, David
Format: Article
Language:English
Subjects:
Aortic dissection
Blood pressure
Cardiology and cardiovascular system
cardiopulmonary exercise testing
Clinical Investigations
Connective tissue diseases
Coronary vessels
Electrocardiography
Exercise
Heart rate
Hemoglobin
Human health and pathology
Hypertension
Life Sciences
Medical prognosis
Morphology
Patients
Physical fitness
prognosis
Pulmonary arteries
Santé publique et épidémiologie
Surgery
Tissues and Organs
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Summary:Background Although recommendations encourage daily moderate activities in post aortic dissection, very little data exists regarding cardiopulmonary exercise testing (CPET) to personalize those patient's physical rehabilitation and assess their cardiovascular prognosis. Design We aimed at testing the prognostic insight of CPET regarding aortic and cardiovascular events by exploring a prospective cohort of patients followed‐up after acute aortic dissection. Methods Patients referred to our department after an acute (type A or B) aortic dissection were prospectively included in a cohort between September 2012 and October 2017. CPET was performed once optimal blood pressure control was obtained. Clinical follow‐up was done after CPET for new aortic event and major cardio‐vascular events (MCE) not directly related to the aorta. Results Among the 165 patients who underwent CPET, no adverse event was observed during exercise testing. Peak oxygen pulse was 1.46(1.22‐1.84) mlO2/beat, that is, 97 (83–113) % of its predicted value, suggesting cardiac exercise limitation in a population under beta blockers (92% of the population). During a follow‐up of 39(20‐51) months from CPET, 42 aortic event recurrences and 22 MCE not related to aorta occurred. Low peak oxygen pulse (
ISSN:0160-9289
1932-8737
DOI:10.1002/clc.23537