The relationship between quantitative epicardial adipose tissue based on CT and coronary artery disease: A protocol for systematic review and meta-analysis

Epicardial adipose tissue (EAT) is a kind of visceral adipose tissue with close proximity to coronary artery and myocardium, which can secrete cell factor, and influence the physiological function and pathophysiological process of myocardium and coronary artery. Clinical imaging diagnosis showed tha...

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Bibliographic Details
Published in:Medicine (Baltimore) 2020-12, Vol.99 (51), p.e23729-e23729
Main Authors: Wu, Baohua, Ren, Zhuanqin, Du, Zhengang, Zhang, Lei, Hou, Bin
Format: Article
Language:English
Subjects:
Adipose Tissue - diagnostic imaging
Adipose Tissue - pathology
Case-Control Studies
Coronary Artery Disease - pathology
Humans
Meta-Analysis as Topic
Pericardium - diagnostic imaging
Pericardium - pathology
Research Design
Study Protocol Systematic Review
Systematic Review as Topic
Tomography, X-Ray Computed
Citations: Items that this one cites
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Summary:Epicardial adipose tissue (EAT) is a kind of visceral adipose tissue with close proximity to coronary artery and myocardium, which can secrete cell factor, and influence the physiological function and pathophysiological process of myocardium and coronary artery. Clinical imaging diagnosis showed that the volume and thickness of EAT exists a certain relevance with coronary artery disease, but it lacked evidence of evidence-based medicine. The research on the implementation of this program will systematically evaluate the relationship of computed tomography (CT) quantitative EAT and coronary artery disease. The English databases (Embase, PubMed, the Cochrane Library, Web of Science) and Chinese database (CNKI, Wanfang, China biomedical database, VIP) of computer retrieval has collected the case control clinical study of relationship between EAT and coronary artery disease from the establishment of the database to October 2020, which was conducted extraction and quality evaluation by 2 researchers independently for data included in the study, and was conducted Meta-analysis for the included literature by adopting RevMan5.3 software. The research evaluated the correlation between EAT and coronary artery disease through the EAT thickness, EAT volume, and other indexes. The research has provided reliable evidence-based evidence for the correlation between CT EAT quantification and coronary artery disease. We will not publish private information from individuals. This kind of systematic review does not involve harming the rights of participants. No ethical approval was required. The results can be published in peer-reviewed journals or at relevant conferences. DOI 10.17605/OSF.IO/DVQNE.
ISSN:0025-7974
1536-5964
DOI:10.1097/MD.0000000000023729