Swine influenza virus: Current status and challenge

•The manuscript has reviewed and discussed current status and challenge of swine influenza virus.•Different swine influenza viruses circulating in pigs globally is a major challenge to produce broadly effective vaccines and control disease.•Enhanced surveillance of IAVs in pigs worldwide is needed t...

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Bibliographic Details
Published in:Virus research 2020-10, Vol.288, p.198118-198118, Article 198118
Main Author: Ma, Wenjun
Format: Article
Language:English
Subjects:
Challenge
Current status
Swine influenza virus
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Summary:•The manuscript has reviewed and discussed current status and challenge of swine influenza virus.•Different swine influenza viruses circulating in pigs globally is a major challenge to produce broadly effective vaccines and control disease.•Enhanced surveillance of IAVs in pigs worldwide is needed to better understand the ecology of IAVs in order to protect animal and public health. Since swine influenza virus was first isolated in 1930, it has become endemic in pigs worldwide. Although large amount of swine influenza vaccines has been used in swine industry, swine influenza still cannot be efficiently controlled and has been an important economic disease for swine industry. The high diversity and varied distribution of different subtypes and genotypes of swine influenza viruses circulating in pigs globally is a major challenge to produce broadly effective vaccines and control disease. Importantly, swine influenza virus is able to cross species barrier to infect humans and even caused influenza pandemic in 2009. Herein, current status and challenge of swine influenza viruses is reviewed and discussed.
ISSN:0168-1702
1872-7492
1872-7492
DOI:10.1016/j.virusres.2020.198118