Efficacy and safety of acupoint injection therapy for allergic rhinitis: A protocol for systematic review and meta-analysis

Allergic rhinitis (AR), characterized by nasal itching, sneezing, and congestion, is a common disorder of nose. In the United States, AR affects 10% to 20% of adults. The negative impact of the high prevalence of AR has caused a great economic burdens worldwide. Modern Western Medicine mainly treats...

Full description

Saved in:
Bibliographic Details
Published in:Medicine (Baltimore) 2020-10, Vol.99 (42), p.e22737-e22737
Main Authors: Chen, Zhenfeng, Xing, Shasha, Huang, Yingzhuan, Zeng, Qifeng, Xu, Donghan, He, Qiumei, Qin, Huangguan, Luo, Xiaofan, Li, Renfeng
Format: Article
Language:English
Subjects:
Acupuncture Therapy
Humans
Meta-Analysis as Topic
Research Design
Rhinitis, Allergic - therapy
Study Protocol Systematic Review
Systematic Reviews as Topic
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Allergic rhinitis (AR), characterized by nasal itching, sneezing, and congestion, is a common disorder of nose. In the United States, AR affects 10% to 20% of adults. The negative impact of the high prevalence of AR has caused a great economic burdens worldwide. Modern Western Medicine mainly treats AR with antihistamine drugs, glucocorticoids, allergic immunotherapy (AIT), but it seriously affects patients compliance because of its long course of treatment, high medical costs and side effect. And now, as an important mean of treating AR, acupoint injection has been widely used in clinics, and has achieved significant efficacy. The following databases will be searched for relevant information before July 2020: PubMed, Embase, Cochrane Library, Web of Science, and CNKI. scores of Rhinitis Quality of Life (RQLQ), Rhinitis Total Symptom Scores (RTSS). Secondary results: levels of antigen-specific serum immunoglobulin E (IgE), total effective rate, adverse event. Data will be collected independently by 2 researchers, and the risk of bias in meta-analysis will be evaluated according to "Cochrane Handbook for Systematic Reviews of Interventions". All data analysis will be conducted using Review Manager V.5.3. and Stata V.12.0. The curative effect and safety of acupoint injection treatment for AR patients will be evaluated systematically. The systematic review of this study will summarize the currently published evidence of acupoint injection treatment for AR to further guide its promotion and application. The private information from individuals will not be published. This systematic review also will not involve endangering participant rights. Ethical approval is not required. The results may be published in a peer-reviewed journal or disseminated in relevant conferences.Open Science Framework (OSF) registration number: https://osf.io/fa9dq.
ISSN:0025-7974
1536-5964
DOI:10.1097/MD.0000000000022737