Magnetic Resonance Spectroscopy of γ-Aminobutyric Acid and Glutamate Concentrations in Children With Attention-Deficit/Hyperactivity Disorder

This cohort study assesses concentrations of γ-aminobutyric acid (GABA) and glutamate in children with attention-deficit/hyperactivity disorder (ADHD) compared with typically developing children.

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Bibliographic Details
Published in:JAMA network open 2020-10, Vol.3 (10), p.e2020973-e2020973
Main Authors: Hai, Tasmia, Swansburg, Rose, Kahl, Cynthia K, Frank, Hannah, Lemay, Jean-François, MacMaster, Frank P
Format: Article
Language:English
Subjects:
Adolescent
Adolescent Development
Attention Deficit Disorder with Hyperactivity - diagnostic imaging
Attention Deficit Disorder with Hyperactivity - metabolism
Brain - diagnostic imaging
Brain - metabolism
Brain Mapping - methods
Case-Control Studies
Child
Cohort Studies
Frontal Lobe - diagnostic imaging
Frontal Lobe - metabolism
gamma-Aminobutyric Acid - metabolism
Glutamine - metabolism
Gray Matter - diagnostic imaging
Gray Matter - metabolism
Gyrus Cinguli - diagnostic imaging
Gyrus Cinguli - metabolism
Humans
Image Processing, Computer-Assisted
Magnetic Resonance Spectroscopy
Online Only
Psychiatry
Research Letter
Temporal Lobe - diagnostic imaging
Temporal Lobe - metabolism
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Description
Summary:This cohort study assesses concentrations of γ-aminobutyric acid (GABA) and glutamate in children with attention-deficit/hyperactivity disorder (ADHD) compared with typically developing children.
ISSN:2574-3805
2574-3805
DOI:10.1001/jamanetworkopen.2020.20973