3PC-004 Automation of parenteral nutrition elaboration in a hospital pharmacy service

BackgroundParenteral nutrition (PN) is a high-risk medication. For this reason quality control must be guaranteed.PurposeTo evaluate the impact of implementing an automated system (Exacta-Mix 2400® Baxa) on the quality of the elaboration of PN.Material and methodsRetrospective study in which a compa...

Full description

Saved in:
Bibliographic Details
Published in:European journal of hospital pharmacy. Science and practice 2018-03, Vol.25 (Suppl 1), p.A25-A25
Main Authors: Blanco-Dorado, S, García-Quintanilla, L, Giraldez-Montero, JM, Gonzalez-Barcia, M, Fernandez-Ferreiro, A, Lamas, MJ
Format: Article
Language:English
Subjects:
Automation
Nutrition
Parenteral nutrition
Pharmacy
Quality control
Section 3: Production and compounding
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:BackgroundParenteral nutrition (PN) is a high-risk medication. For this reason quality control must be guaranteed.PurposeTo evaluate the impact of implementing an automated system (Exacta-Mix 2400® Baxa) on the quality of the elaboration of PN.Material and methodsRetrospective study in which a comparative gravimetric control was performed between the PNs in the first week of December 2015 (manual procedure) and the same week one year later with the automated system.Gravimetric control is a strategy used for the quality control in the elaboration of PN. It consists of comparing the real weight with the theoretical weight (calculated according to the volume and density of each of its components). The gravimetric error was calculated as a percentage compared to the theoretical weight. Regulatory agencies establish an acceptable margin of error of 5%, and advise reducing it to 3%, especially in paediatric nutrition. The deviations from the theoretical weight and the percentage of preparations that exceeded 3% were analysed. For the comparison of means of deviation, a K-W test was performed using software R.Tricameral nutrition was excluded from the study because it is already elaborated and does not require manipulation.ResultsOne hundred and fourty-four PNs (77 manuals and 77 automated) were analysed.The mean variation of the actual weight with respect to the theoretical weight was 3.37% and 0.73% with the manual and automated procedure respectively (p
ISSN:2047-9956
2047-9964
DOI:10.1136/ejhpharm-2018-eahpconf.56